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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNRC6B
All Species:
21.52
Human Site:
S222
Identified Species:
59.17
UniProt:
Q9UPQ9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPQ9
NP_001020014.1
1833
194002
S222
T
T
D
N
N
S
A
S
N
P
G
S
E
K
S
Chimpanzee
Pan troglodytes
XP_510885
2108
226554
S303
K
F
V
V
G
S
S
S
N
N
V
G
H
G
S
Rhesus Macaque
Macaca mulatta
XP_001101111
1722
182483
N182
S
N
N
G
T
S
P
N
P
I
H
I
W
D
K
Dog
Lupus familis
XP_538361
1779
188477
S222
T
T
D
N
N
S
A
S
N
P
G
S
E
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKI2
1810
191944
S259
T
T
D
N
N
S
A
S
N
P
G
S
E
K
S
Rat
Rattus norvegicus
NP_620200
1818
192846
S258
T
T
D
N
N
S
A
S
N
P
G
S
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505551
1935
205191
S223
M
D
T
D
S
A
S
S
S
G
S
E
K
N
L
Chicken
Gallus gallus
XP_416246
1768
187625
S223
T
T
D
N
N
S
A
S
N
P
G
L
E
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663990
2011
204523
G241
G
T
G
G
T
D
S
G
A
I
L
N
C
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.7
93.4
94.4
N.A.
93.1
92.8
N.A.
39.4
87.2
N.A.
41.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.2
93.6
95.3
N.A.
94.8
94.4
N.A.
53.5
91.2
N.A.
54
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
6.6
100
N.A.
100
100
N.A.
6.6
86.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
26.6
100
N.A.
100
100
N.A.
46.6
93.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
56
0
12
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
12
56
12
0
12
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
12
56
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
12
23
12
0
0
12
0
12
56
12
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
23
0
12
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
0
0
12
56
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
12
56
56
0
0
12
67
12
0
12
0
23
12
% N
% Pro:
0
0
0
0
0
0
12
0
12
56
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
12
78
34
78
12
0
12
45
0
0
56
% S
% Thr:
56
67
12
0
23
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
12
0
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _